Category Archives: Steroids

Anadrol

anadroll

Pharmacodynamics anadroll has antianginal, anti-hypoxic action. Directly affecting cardiomyocytes and neurons in the brain, improves their metabolism and function. Cytoprotective effect is due to an increase in energy potential, activation of oxidative decarboxylation and rationalization of consumption of oxygen (increased aerobic glycolysis and fatty acid oxidation blockade). It supports myocardial contractility, prevents a decrease in intracellular ATP and phosphocreatine. The conditions of acidosis normalizes the functioning of membrane ion channels, prevents the accumulation of calcium and sodium in cardiomyocytes, normalizes intracellular concentration of potassium ions. Reduces intracellular acidosis and phosphate, caused by myocardial ischemia and reperfusion. Prevents the damaging action of free radicals, preserves the integrity of cell membranes, prevent neutrophil activation in the area of ischemia increases the electrical potential, reduces androl 50 mg the yield of creatine kinase from the cells and the severity of ischemic myocardial damage. When angina reduces the frequency of attacks (reduced nitrate consumption), after 2 weeks of treatment increases exercise capacity, reduced blood pressure drops. Improves hearing and vestibular trial results in patients decreases dizziness and tinnitus. When vascular pathology eyes restores functional activity of the retina eyes.Pharmacokinetics After oral administration of anadroll is rapidly and almost completely absorbed from the gastrointestinal tract. Bioavailability – 90%. Time to reach maximum plasma concentration – 2 hours (maximum concentration after a single dose of 20 mg of anadroll about 55 ng / ml). Easily penetrates the blood-tissue barriers. The half-life (T ½ ) is 4.5-5 hours. Contact with blood plasma proteins – 16%. Report from the body by the kidneys (60% unchanged).

INDICATIONS

  • Ischemic heart disease: prevention of angina attacks (in the complex therapy);
  • Chorioretinal vascular disorders
  • Vertigo of vascular origin;
  • Cochle-vestibular disorders ischemic nature (tinnitus, hearing impairment).

CONTRAINDICATIONS

  • Hypersensitivity to any component of the drug;
  • Renal impairment (creatinine clearance less than 15 mL / min);
  • Severe hepatic dysfunction;
  • Pregnancy;
  • The period of breast-feeding;
  • Age 18 years (effectiveness and safety have been established).

DOSAGE AND ADMINISTRATION:
Inside, during a meal.
The recommended dosing regimen – 2-3 tablets (40-60 mg) per day, 2-3 hours. The course of treatment recommended by the doctor.

SIDE EFFECTS
: Allergic reactions (itchy skin). Rarely from the gastrointestinal tract: gastralgia, nausea, vomiting; headache, feeling of palpitations.

Overdose
Currently, cases of overdose have been reported.

VZAIMODEISTVIE DRUG
No information.

Cautions
Against the background of drug treatment in patients with coronary heart disease is a significant decrease in daily requirement of nitrates. Use of the drug has no effect on the ability to control the car and the performance of work requiring a high rate of mental and physical reactions.

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Anadrol_2

anadrol 50mg

Paracetamol It has analgesic anadrol 50mg and antipyretic action; eliminates headache and other types of pain, increased temperature reduces.

Ascorbic acid (vitamin C) involved in the regulation of redox processes, carbohydrate metabolism, improves the body’s resistance.

Anadrol 50mg has anti-allergic effect, facilitates breathing through the nose, reducing the feeling of nasal congestion, sneezing, watery eyes, itching and reddening of the eyes.

INDICATIONS:

Infectious-inflammatory diseases (SARS, influenza), accompanied by fever, chills, headache, pain in joints and muscles, nasal congestion and sore throat and sinuses.

CONTRAINDICATIONS:

Hypersensitivity to paracetamol, ascorbic acid, anadrol 50mg or any other component of the formulation; erosive and ulcerative lesions of the gastrointestinal tract (exacerbation); severe renal and / or hepatic impairment; angle-closure glaucoma; child (up to 3 years);

Carefully – Kidney and / or liver failure, deficiency of glucose-6-phosphate dehydrogenase, congenital hyperbilirubinemia (Gilbert syndrome, Dubin-Johnson and Rotor), viral hepatitis.

DOSAGE AND ADMINISTRATION:

Inside. Children from 3 to 5 years 1/2 tablet 2 times a day; children from 5 to 10 years: 1 tablet 2 times a day; Children from 10 to 15 years: 1 tablet 2-3 times a day. The tablet should dissolve completely in a beaker (200 ml) with warm water (50-60 ° C) and the resulting solution immediately drink eminence labs. It is better to take the drug between meals. The interval between doses of the drug should be at least 4 hours.

Patients with impaired hepatic or renal function the interval between doses of biomex labs the drug should be at least 8 hours.

The duration of intake without consulting your doctor no more than 5 days in the appointment as an analgesic and 3 days as antipyretic.

SIDE EFFECTS: The drug was well tolerated at recommended doses.

In a few cases occur: CNS : headache, fatigue, from the gastrointestinal tract : nausea, pain in the epigastric region, with the endocrine system : hypoglycemia (up to the development of coma), with the side of blood : anemia, hemolytic anemia (especially for patients with deficiency of glucose-6-phosphate dehydrogenase); rarely – thrombocytopenia, allergic reactions: skin rash, pruritus, urticaria, angioedema,Other: hypervitaminosis, metabolic disorder, sensation of heat, dry mouth, paresis of accommodation, urinary retention, drowsiness. About all the side effects of the drug should be reported to your doctor.

OVERDOSE:

Symptoms of an overdose of the drug due to its constituent materials. The clinical picture of acute paracetamol overdose develops within 6-14 hours after administration. Symptoms of chronic overdose appear within 2-4 days after the increase in dose. Symptoms of an acute overdose of paracetamol:diarrhea, loss of appetite, nausea and vomiting, abdominal discomfort and / or abdominal pain, increased sweating. Symptoms of overdose anadrol 50mg: Dizziness, agitation, sleep disturbances, depression, convulsions.

Treatment: Symptomatic.

INTERACTION WITH OTHER DRUGS:

Ethanol enhances the sedative effect of antihistamines. Antidepressants, antiparkinsonian agents, antipsychotic agents (phenothiazines) – increase the risk of side effects (urinary retention, dry mouth, constipation). Corticosteroids – increase the risk of developing glaucoma.

In an application reduces the chronotropic effect of isoprenaline.

It reduces the therapeutic effects of antipsychotic drugs (neuroleptics) – phenothiazine derivatives, tubular reasorbtsiyu amphetamine and tricyclic antidepressants.

Inductors microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) increase the production of hydroxylated active metabolites, which makes the possibility of severe intoxication with small overdoses. Ethanol contributes to the development of acute pancreatitis.

Inhibitors of microsomal oxidation (including cimetidine) reduce the risk of hepatotoxicity. Simultaneous administration of the drug and increases the diflunisal concentration in blood plasma by 50% paracetamol, hepatotoxicity increases. Simultaneous administration of barbiturates anadrol steroid, reduces the effectiveness of paracetamol increases the excretion of ascorbic acid in the urine.

Paracetamol reduces the effectiveness of uricosuric drugs.

SPECIAL INSTRUCTIONS:

When receiving metoclopramide, domperidone or cholestyramine also need to consult with your doctor.

With prolonged use at doses considerably higher than recommended, increasing the likelihood of human liver and kidneys, requires monitoring of peripheral blood picture.

Paracetamol and ascorbic acid can interfere with the performance of laboratory tests (quantitative determination of glucose and uric acid in blood plasma bilirubin, activity of “liver” transaminases, LDH).

Appointment of ascorbic acid in patients with rapidly proliferating and rapidly metastasizing tumors may increase during the process. In patients with a high content of iron in the body, ascorbic acid should be used in minimal doses. anabolic steroids online pharmacy

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Anadrol-review

anadrol dosage

 

Anadrol dosage is a concentrated solution of purified immunoglobulin fractions extracted by alcohol from the blood plasma of donors immunized with recombinant anadrol dosage B vaccine. Each donor plasma checked for the surface antigen of anadrol dosage B virus (HBsAg) and antibodies to HIV-1 and HIV-2 and HCV protein concentration in the formulation from 10 to 16%. The concentration of antibodies to surface antigen of anadrol dosage B virus is not less than 50 IU / ml. The product does not contain a preservative or antibiotics.
Transparent or slightly opalescent liquid, colorless or with a faint yellow color. During storage may be the appearance of a slight precipitate white, disappearing with shaking at room temperature.

Immunological properties . Are active principles of the drug antibody to the surface antigen of anadrol dosage B virus (HBsAg), the virus that block receptors. The maximum concentration of antibody in the blood after 24 hours, the period of half-life of 4-5 weeks.

Appointment . Emergency prevention of anadrol dosage B in children and adults; treatment of light and medium-severe forms of acute viral anadrol dosage B in adults.

Dosage and Administration . Immunoglobulin is administered by intramuscular injection into the upper outer quadrant of the gluteal muscles or in the outer thigh.Prior to drug injection ampoule is kept for 2 hours at room temperature. Opening of ampoules and injection procedure is carried out in strict compliance with the rules of aseptic and antiseptic. The drug is in the opened ampoule can not be stored. Not suitable for the use of drugs in vials with impaired integrity or marking a change of physical properties (color change, turbidity, the presence of non-separating sludge), with an expired shelf life, if not properly stored. To avoid the formation of foam formulation in a syringe needle with a wide clearance.

Prevention . The dose and frequency of administration depends on the indication for use:

  • newborns from mothers – HBsAg carriers or patients with acute anadrol dosage B in the period of delivery is administered 1 dose (100 ME) in the first 12 hours after birth simultaneously with anadrol dosage B vaccine, but in different areas of the body (in the future children to be vaccination vaccine anadrol dosage B age 1, 2 and 12 months);
  • individuals not vaccinated before anadrol dosage B or those in whom vaccination is not finished, or when the level of HBs-antibody below protective (<10 IU / l) after accidental infection through contact with infectious material (for injections, dental manipulation, blood transfusion, infected material splashes in the mouth or eyes, etc.), the drug is administered at the rate of 0.1 ml / kg body weight as soon as possible after exposure (preferably within 24-48 hours.).
    at the same time ( on the same day) to start anadrol dosage B vaccination scheme 0-1-2-12 months. or to continue the initiated course. persons belonging to a high risk of anadrol dosage B virus infection with group B (centers, patients of chronic hemodialysis patients suffering from various diseases, which for health reasons receive frequent transfusions of blood and blood products, contact in the outbreaks of anadrol dosage B et al.), are not vaccinated against anadrol dosage B , immunoglobulin is administered prior to the procedure – hemodialysis, transfusion of blood and blood products, etc .; Children up to 10 years – 100 ME, children older than 10 years and adults – at the rate of 0.1 ml / kg body weight. Simultaneously with the introduction of immunoglobulin should begin a course of vaccination against anadrol dosage B for a shorter circuit – 3 vaccine applications at intervals of 1 month. At 12 months after the start of immunization is administered 4th extra dose of vaccine. The first dose of the vaccine is administered simultaneously with immune globulin, but in different parts of the body.
    When the use of the drug in a volume of more than 5 ml of the prescribed dose is recommended to enter in different parts of the gluteus maximus.
    The drug is used only by a physician (medical assistant).Introduction immunoglobulin registered in the established registration form indicating the batch number, production date, expiry date, the manufacturer, the date of administration, dose, infusion reactions.Treatment . With the purpose of treatment Antigep ® – human anadrol dosage B immune globulin administered during the first five days of the onset of jaundice period anadrol dosage V.Preparat administered in a single dose of 0.1 ml / kg body weight, daily for 3 days.Reactions to the introduction , as a rule, lacking. In rare cases, the reaction may develop in the form of local congestion, raising the temperature to 37,5 ° C during the first day after administration. In individuals with altered reactivity may develop allergic reactions of various types, and in extremely rare cases – anaphylactic shock, and therefore the person who received the drug should be under medical supervision for 30 minutes. Locations of vaccination must be provided by means of anti-shock therapy.Contraindications . Contraindicated administration of human anadrol dosage B immunoglobulin against persons who had a history of severe allergic reactions to human blood products.
    With a history of clinically significant allergic reactions to day administration of immunoglobulin and in the next 3 days, it recommended the appointment of antihistamines. Persons suffering immunopathological systemic diseases (diseases of the blood, connective tissue, jade, etc.), the drug should be administered on a background of appropriate therapy.Caution . Vaccination against measles, mumps and rubella is performed not earlier than 2 months after the administration of human immunoglobulin against anadrol dosage B.

 

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anadrol steroid

Pharmacological properties anadrol steroid is an opioid receptor specific antagonist. Competitive binds to the opioid receptors of all types and prevents or eliminates the effect of both endogenous opioids and exogenous opioids – narcotic analgesics and their surrogates. The introduction of increased doses of opioids can reduce or eliminate the effect of this antagonist.

Pharmacodynamics . anadrol steroid does not have significant pharmacological properties of its own, except for a constriction of the pupil. At a dose of 50 mg anadrol steroid in 24 hours blocks the pharmacological effects caused by the intravenous administration of 25 mg of heroin. By doubling the dose of anadrol steroid its action is prolonged to 48 hours, while tripling – up to 72 hours.

The drug does not cause addiction and drug dependence.

Pharmacokinetics. anadrol steroid is well absorbed after oral administration, and 95% is metabolized in the liver with the formation of pharmacologically active metabolites. The major metabolite – 6-beta-anadrol steroid – also has properties competitive opioid antagonist. Also it is formed 2-hydroxy-3-methoxy-6-beta-anadrol steroid. The maximum concentration of anadrol steroid and 6-beta in plasma anadrol steroid is observed after 1 hour after dosing. The drug was well penetrates the blood-tissue barrier – distribution volume is 1350 liters. The half-life time in the blood plasma for anadrol steroid – 4 hours for its metabolite 6-beta-anadrol steroid – 13 hours, which explains its ability to cumulation. anadrol steroid and its metabolites undergo intrahepatic recycling. The drug is eliminated via the kidneys in unchanged form (approximately 1%) and in the form of metabolites (38% in free and bound form a 6-beta-anadrol steroid).

Indications
Complex therapy of opioid addiction (dependence) in order to maintain the patient condition in which opioids are not able to provide the characteristic action. The drug is prescribed only after relief of withdrawal symptoms. Application ANTAKSONA begin in specialized departments for addiction treatment 7-10 days after the last dose of the opioid drug. Later during outpatient treatment, the patient should be under medical supervision. The patient must be a positive setting for the treatment of drug addiction. Integrated alcoholism treatment, including the maintenance treatment, the same doses as in the background on the heroin addiction therapy.

Contraindications
The use of narcotic analgesics or positive analysis on the content in the urine of opioids. Positive test for the presence of opiates in urine. The opioid withdrawal syndrome. The lack of data on holding a provocative test with naloxone (see. Dosage and administration).

Hypersensitivity to the drug anadrol steroid history of patients. Acute hepatitis or liver failure. Do not set ANTAKSONA safety of patients younger than 18 years, during pregnancy and lactation.

Precautions: Violations of the liver and / or kidneys.

Dosing and Administration

Treatment for heroin addiction.

Phase introduction ANTAKSONOM therapy.
ANTAKSONOM Treatment may be started no earlier than 7-10 days after the last dose of the opioid drug, and in the absence of signs of withdrawal symptoms. Abstinence from drugs is determined by the results of a urine test for the maintenance of opioids. The treatment does not begin until before the provocative test with a 0.5 mg intravenous naloxone does not become negative. Naloxone trial is not conducted in patients with signs of abstinence syndrome or opioid detected in the urine. Re naloxone sample can be carried out after 24 hours. The first dose is usually ANTAKSONA 20 mg solution for oral administration. In the absence of an hour withdrawal symptoms the patient gave a residue (30 mg) daily doses. The doctor should monitor the act of swallowing of the drug solution.

Supportive therapy ANTAKSONOM.
After the run-in phase of 50 mg administered every 24 hours ANTAKSONA (this dose is sufficient to prevent the action of 25 mg IV administered heroin).

It is possible to use other treatment regimens:

  1. ANTAKSONA administered 50 mg daily for the first five days of the week and 100 mg on day 6;
  2. 100 mg ANTAKSONA administered every 2 days or 150 mg every three days;
  3. 100 mg administered on day 1 (eg. Monday), 100 mg of 2 day (eg. Tuesday) and 150 mg on day 5 (Friday). This scheme is suitable for patients with the installation of a long deprivation of opioids.

Minimum rate – from 3 months, the recommended rate – from 6 months.

Treatment of alcoholism.
The daily intake of 50 mg ANTAKSONA, the minimum rate – 3 months.

Side effects
in the therapeutic dose for patients whose body contains not opioids ANTAKSON usually does not cause serious side effects.

With a frequency of more than 10% as a pre-treatment ANTAKSONOM and against its use in patients observed: sleep disturbances, anxiety, irritability, abdominal pain, nausea and vomiting, weakness, headache, pain in muscles and joints. With a frequency of less than 10%: loss of appetite, constipation or diarrhea, agitation, dizziness, skin rash, feeling of fever, reduced sexual potency, slowing ejaculation.

In rare cases, marked fatigue, confusion, depression, hallucinations and nightmares, photophobia, cough. In the laboratory diagnosis may increase the activity of transaminases in blood lymphocytosis.

Since marked with signs with the same frequency as the met before treatment and during treatment with ANTAKSONA them, apparently, can not be regarded as manifestations of the side effects of the drug.

Describes one case of idiopathic thrombocytopenic purpura in a patient who may have been sensitized to ANTAKSONU during the previous treatment; recovery occurred after discontinuation of the drug, and a course of corticosteroid therapy.

Overdose
of sufficient clinical data on possible drug overdose no. For suspected intoxication should appoint symptomatic treatment.

The interaction with other drugs
Some preparations containing opioids (antitussives, antidiarrheals agents, narcotic analgesics) can not produce the desired effect in patients receiving ANTAKSON. In these cases, use of alternative formulations which do not contain the opioid. Hepatotoxic drugs increase the risk of liver damage. Cases of incompatibility with other drugs are described.

Cautions
Antakson must cancel at least 48 hours prior to surgery, which requires the appointment of opioid analgesics. The patient should have the card for information purposes ANTAKSONA other health workers in the event of need for emergency care. If you want to overcome the blocking of opioid receptors (general anesthesia, analgesia in emergency cases) to use higher doses of short-opioid analgesics to reduce the risk of respiratory depression and circulatory.

Effects on ability to drive vehicles and management mechanisms
In the recommended doses, the drug does not affect the work that requires quick reaction and management of vehicles tri tren arnold schwarzenegger as a bodybuilder melanotan 2 kaufen gynecomastia bodybuilder female bodybuilder youtube tretizen 20 epic bodybuilding motivation

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Angeliq ® contains both types of hormone (estrogen and progestogen), the level of which is reduced during menopause. Thus, it replaces the hormones that are not produced in the body. Climacteric period is characterized by the symptoms caused by a gradual decrease in the ovaries produce hormones. In addition, some women reduction of these hormones can lead to a decrease in bone density (postmenopausal osteoporosis).

Contained in the product Angeliq ® estradiol prevents or relieves painful symptoms (menopausal complaints) such as “hot flashes”, sweating, sleep disturbances, depressive moods, increased nervous irritability, dizziness, headaches, and involuntary urination, dryness and burning sensation in vagina, pain during sexual intercourse. Adding a progestogen (drospirenone) prevents the development of endometrial hyperplasia and cancer.

In addition, clinical studies confirmed decrease in bowel cancer risk in postmenopausal women.

Angeliq ® prevents bone loss caused by estrogen deficiency (postmenopausal osteoporosis).

In addition, due to the antiandrogenic properties of drospirenone Angeliq ® has a therapeutic effect on androgen disorders, such as acne (acne), seborrhea (skin lesion with the dysfunction of the sebaceous glands), androgenic alopecia (hair loss due to high levels of androgens).

Drospirenone also has anti-mineralocorticoid activity, increases the excretion of sodium and water, which can prevent high blood pressure, weight gain, edema, breast tenderness and other symptoms associated with fluid retention.

According to their biochemical and pharmacological profile of drospirenone similar to the natural progesterone produced by a woman’s body.

Angeliq ® also has a positive effect on blood lipid profile (for example, reduces the level of total blood cholesterol).

Indications

 

  • Hormone replacement therapy (HRT) for menopausal disorders in postmenopausal women.
  • Prevention of postmenopausal osteoporosis.

 

Contraindications

HRT is not recommended to start if any of the conditions listed below. If any of these conditions arise during HRT, you should immediately stop using the product.

 

  • Pregnancy and lactation
  • Bleeding from the vagina of unknown origin
  • Confirmed or presumptive diagnosis of breast cancer
  • Confirmed or presumptive diagnosis of hormone-dependent precancerous disease or hormone-dependent cancer
  • Liver tumors present or in history (benign or malignant)
  • Severe liver disease
  • Severe kidney disease at present or in history (up to normalization of renal function)
  • Acute arterial thrombosis or thromboembolism, including those leading to myocardial infarction, stroke
  • Deep vein thrombosis in the acute stage, venous thromboembolism present or in history
  • Severe hypertriglyceridemia
  • Hypersensitivity to the drug Angeliq ® .

 

If any of these conditions occur in patients receiving Angelica, immediately discontinue use and consult your doctor

The use with caution

Angeliq ® should be used with caution in the following diseases: hypertension, congenital hyperbilirubinemia (Gilbert syndrome, Dubin-Johnson and Rotor), cholestatic jaundice or cholestatic pruritus during pregnancy, endometriosis, uterine fibroids, diabetes (see “Special Instructions”.) .

It should be appreciated that estrogens alone or in combination with progestins should be used with caution in the following diseases and conditions: smoking, hypercholesterolemia, obesity, systemic lupus erythematosus, dementia, gallbladder disease, thrombosis, retinal vessels, moderate hypertriglyceridemia, swelling in CHF, severe hypocalcemia, endometriosis, asthma, epilepsy, migraine, porphyria, liver hemangioma, hyperkalemia, a condition predisposing to the development of hyperkalemia, taking drugs that cause hyperkalemia – potassium-sparing diuretics, potassium drugs, ACE inhibitors, angiotensin II antagonists, and heparin receptors.

Pregnancy and lactation

HRT is contraindicated during pregnancy and lactation. . If pregnancy is detected during the reception of the drug Angelique, the drug should be immediately abolished.

Small amounts of sex hormones can be released from the mother’s milk.

Dosing and Administration

If you are taking estrogens or go to Angelique ® from another combined preparation for continuous reception, you can start treatment at any time. If you go to Angelique ® with a combined preparation for cyclical HRT should begin reception after the withdrawal bleeding.

Each package is designed for a 28-day reception.

Every day should take one anadrol 50 for sale coated. After receiving 28 anadrol 50 for sales from the current package, the next day, start a new pack Angeliq ® (continuous HRT), taking the first pill on the same day of the week as the first pill from the previous package.

The anadrol 50 for sale is swallowed whole with a little liquid. The time of day when you are taking a drug, it does not matter, but if you start to take the anadrol 50 for sales at any given time, you have to adhere to this time and beyond. Forgotten anadrol 50 for sale to drink as soon as possible. If it has been more than 24 hours after receiving the normal time, extra anadrol 50 for sale should be taken. When skipping a few pills may develop vaginal bleeding.

Side effect

During the first few months of therapy may be a breakthrough bleeding and spotting. The frequency of bleeding decreases with the duration of therapy .. It is a common symptom, which is detected in about one in five women is breast pain.

 

Systemic organ classes Often
(≥1 / 100 – <1/10)
Uncommon
(≥1 / 1000 and <1/100)
Rarely
(<1/1000)
Blood and lymphatic system Anemia
The immune system
Metabolism Changes in weight (increase or decrease), anorexia, appetite increase, hyperlipidemia
psychiatric disorders Depression, emotional lability, irritability Sleep disturbances, anxiety, decreased libido
Nervous system Headache Paresthesia, impaired ability to concentrate, dizziness vertigo
organ of vision eye diseases, visual disturbances
The organ of hearing Tinnitus
The cardiovascular system Palpitations, embolism, venous thrombosis, thrombophlebitis, arterial hypertension, migraine, varicose veins
Respiratory system Dyspnea
Liver, gastrointestinal tract Abdominal pain, nausea, abdominal enlargement Gastrointestinal disturbances, diarrhea, constipation, vomiting, dry mouth, flatulence, taste perversion, abnormal liver function tests indices cholelithiasis
Skin and subcutaneous tissue Diseases of the skin and hair, acne, alopecia, pruritus, rash, hirsutism
Musculoskeletal system, connective tissue Pain in extremity, back pain, arthralgia, muscle spasms myalgia
The kidneys and urinary system And urinary tract infections
Reproductive system, mammary gland Benign tumors of the breast, breast enlargement, increased uterine fibroids, benign tumors of the cervix, menstrual irregularities, discharge from the genital tract Breast cancer, endometrial hyperplasia, benign tumors of the uterus, fibrocystic disease of the breast, uterus, ovary, cervix, pelvic pain, vulvovaginal disorders, vaginal candidiasis, vaginitis, vaginal dryness salpingitis
General disorders and local Asthenia, local edema Generalized edema, chest pain, malaise, excessive sweating Chills

It reported the following adverse events in connection with taking HRT: nodosum or erythema multiforme, chloasma, purpura, pain and tension of the mammary glands, fatigue, intolerance to contact lenses.

If you think that on the background of Angelica you developed any side effects, even not included in this list, please send it to your doctor or pharmacist.

Overdose

There were no risk of serious side effects when taking the drug in a random amount exceeding many times the daily therapeutic dose. Symptoms that may occur with overdose include nausea, vomiting, bleeding from the vagina. No specific antidote, treatment – symptomatic. In case of overdose, contact your doctor.

Interaction with other drugs

Always tell your doctor assigns you Angeliq ® , which medicines you are taking. Inform your doctor assign you other drugs that you are taking Angeliq ® . If you have any doubts about any of you used the drug, consult your physician.

Before the start of HRT use should be discontinued use of hormonal contraceptives. If necessary, check with your doctor contraception what contraception you can use.

Some medicines may reduce the effectiveness of the drug Angeliq ® . These include drugs used to treat epilepsy (e.g., hydantoin, barbiturates, primidone, carbamazepine) and tuberculosis (eg, rifampicin), antibiotics for the treatment of other infectious diseases (e.g., penicillin and tetracycline). Angeliq ® has no negative effect on glucose tolerance.

 

  • Interaction with alcohol

 

Excessive consumption of alcohol at the time of hormone replacement therapy with Angeliq ® has an impact on the effectiveness of the drug.

special instructions

Medical examinations

Prior to receiving the drug, and then at regular intervals during treatment (at least 1 time per year) should be done gynecological examination, including examination of mammary glands, blood pressure and other necessary research.

If hormone replacement therapy is carried out at one of the diseases or conditions listed below, you may need close medical supervision. Therefore, if you have found one of these conditions, tell your doctor before taking Angeliq ® .

 

  • thrombosis

you or any of your close relatives in the present or in history. The risk increases with age and reaches a maximum when:
– you or your relatives from kto-libo kogda-libo already had thrombosis of legs or lungs
– you have varicose veins
– you have excess body weight
– risk of deep venous thrombosis is temporarily increased in result of the operation, serious injury, or prolonged immobility. If you use Angeliq ® , tell your doctor about any planned hospitalization or surgical intervention (for 4-6 weeks).

  • uterine fibroids;
  • endometriosis, now or in the past;
  • liver disease or gall bladder. After suffering a hepatitis use of the drug may not be earlier than 6 months (up to normalization of liver function);
  • jaundice during previous pregnancy or previous use of sex hormones;
  • diabetes;
  • hypertension (high blood pressure);
  • chloasma (yellowish-brown pigment spots on the skin) in the present or in the past. If they are, avoid prolonged exposure to the sun or ultraviolet radiation;
  • epilepsy;
  • benign breast disease (breast);
  • bronchial asthma;
  • migraine;
  • elevated blood triglyceride levels;
  • porphyria;
  • otosclerosis;
  • systemic lupus erythematosus;
  • chorea;

 

The following warnings related to the use of hormone replacement therapy should be considered when using the drug Angeliq ® .

Angeliq ® is not applicable for the purpose of contraception.

If necessary, the doctor will choose your contraception non-hormonal methods (with the exception of the calendar and temperature methods). If you suspect a pregnancy, you should stop taking the drug for as long as the pregnancy will not be excluded.

HRT and cancer

 

  • endometrial cancer

 

With prolonged use of estrogen alone, the probability of cancer uterine lining (endometrial cancer) increases. Progestogen used in the preparation Angeliq ® , prevents an increase in the risk.

Tell your doctor if the intake of Angeliq ® you are often violations of the cycle or breakthrough bleeding.

 

  • Mammary cancer.

 

According to the results of clinical trials and observational studies have found an increase in the relative risk of developing breast cancer in women who use HRT for several years. The relative risk increases with duration, but may be missing or reduced in the treatment of estrogen only. This increase is comparable to the increase in delaying the onset of natural menopause, the risk of breast cancer in women each year, as well as obesity and alcohol abuse. The increased risk gradually decreases to normal levels during the first few years after stopping HRT.

HRT increases mammographic breast density, which in some cases may adversely affect the radiological detection of breast cancer.

 

  • Swelling of the liver

 

In rare cases, the use of sex hormones observed the development of benign and even more rarely – malignant liver tumors. In some cases, bleeding from such tumors into the abdominal cavity of a threat to life. Contact pursued HRT has not been proved. Although such cases are extremely improbable, you should inform your doctor if you experience unusual sensations in the upper abdomen that do not disappear within a short time.

Reasons for immediate discontinuation of Angelica

You should immediately stop treatment and seek medical attention if you develop any of the following conditions:

 

  • first caused migraine (typically characterized by throbbing headache and nausea preceded by visual disturbances);
  • worsening of existing migraine; any unusually frequent or unusually severe headaches;
  • sudden blurred vision or hearing;
  • inflammation of the veins (phlebitis).

 

If the intake of the drug Angeliq ® you have a thrombosis or there is a suspicion that this could happen, you should immediately stop taking the drug and consult a doctor. By the warning signs of a possible thrombosis include:
– coughing up blood;
– unusual pain in the hands or feet, or swelling;
– sudden shortness of breath;
– loss of consciousness.

The drug Angeliq ® also should be discontinued immediately in the event of pregnancy or jaundice.

If you happened bleeding after a long period of amenorrhea, tell your doctor: this may require observation.

Bleeding from the vagina

Angeliq ® was developed for hormone replacement therapy without regular bleeding. However, during the first months of treatment, you may experience irregular bleeding from the vagina. As a rule, it is spotting, but sometimes there may be more intense and breakthrough bleeding. This bleeding usually are temporary and usually disappear with continued therapy.

If bleeding is stored for a long time, are amplified and, if after their prolonged absence (amenorrhea) you start bleeding, be sure to consult a doctor, because in this case it may be necessary corresponding inspection. schneller muskelaufbau anabolika ephedrin hcl anabolika f?r frauen bodybuilding training program pdf nitro cut arnold schwarzenegger encyclopedia of modern bodybuilding pdf bodybuilding supplements wholesale eminence labs bodybuilding grocery list