It has analgesic, antipyretic and weak anti-inflammatory activity, the mechanism of which is associated with inhibition of prostaglandin synthesis. It is pyrazolone derivative.  When intravenous: onset of action Рwithin 5-10 minutes, the maximum effect Рafter 5-30 minutes duration Рup to 2 hours. It is metabolized in the liver, small concentration constant anadrol detected in plasma, excreted by the kidneys. At therapeutic doses, it penetrates into breast milk.

Pain (mild to moderate severity): including: neuralgia, myalgia, arthralgia, biliary colic, intestinal colic, renal colic, injury, burns, decompression sickness, shingles, orchitis, sciatica, myositis, postoperative pain, headache, toothache, tuberculosis. Feverish syndrome (infectious and inflammatory diseases, insect bites -. Mosquitoes, bees, horseflies, etc., post-transfusion complications).
The drug is intended for symptomatic therapy reduce pain and inflammation at the time of use, does not affect the progression of the disease.

: Hypersensitivity to pyrazolone derivative (phenylbutazone, tribuzon), a tendency to bronchospasm.
Severe hepatic dysfunction and / or kidney disease, deficiency of glucose-6-phosphate dehydrogenase, blood diseases, blood oppression (agranulopitoz, cytostatic or infectious neutropenia), and – anemia and leukopenia. Bronchial obstruction, rhinitis, urticaria provoked by taking aspirin or other nonsteroidal anti-inflammatory drugs (including a history..), Active liver disease, condition after coronary artery bypass surgery; confirmed hyperkalemia, erosive and ulcerative changes in gastric mucosa and 12 duodenal ulcer, active gastrointestinal bleeding, inflammatory bowel disease. Infants up to 3 months.
Use during pregnancy and lactation.
Do not use during pregnancy (especially during the first 3 months and 6 weeks) and lactation.

Coronary heart disease, chronic heart failure, cerebrovascular disease, dyslipidemia / hyperlipidemia, diabetes mellitus, peripheral arterial disease, smoking, creatinine clearance less than 60 mL / min. a history of the development of ulcerative lesions of the gastrointestinal tract, the presence of H. pylori infection, old age, long-term use of nonsteroidal anti-inflammatory drugs, severe somatic diseases, concomitant use of oral corticosteroids (in Vol. h. prednisone), anticoagulants (in Vol. h. warfarin), antiplatelet agents (in T. Ch acetylsalicylic acid, clopidogrel), selective serotonin reuptake inhibitors (as Charles T. citalopram, fluoxetine, paroksetip, sertraline).
Special care is required when assigning patients with systolic blood pressure below 100 mm Hg . Art. or circulatory instability (eg in myocardial infarction, multiple trauma commencing shock), with indications of a history of renal diseases (pyelonephritis, glomerulonephritis) and long-term history of alcohol.

Dosing and dose
preparation administered in / (in severe pain) or / m at 1 – 2 ml 250 mg / ml or 500 mg / ml of solution 2-3 times a day, but no more than 2 grams per day.
Babies administered of 0.1 – 0.2 ml 500 mg / ml or 0.2 -. 0.4 ml of 250 mg / ml per 10 kg body weight 2-3 times a day
for children up to 1 year of drug administered only V / m, the rate of no more than 3 days.

Side effects:
At therapeutic doses, the drug was well tolerated. In applying the drug in individual patients may experience side effects: allergic reactions (skin rash, angioedema, rare anaphylactic shock, Stevens-Johnson syndrome and Lyell, bronchospasm); long-term use can cause agranulocytosis, leukopenia, thrombocytopenia, hypotension, interstitial nephritis. Impaired renal function, oliguria, anuria, proteinuria, urine staining in red.
When the propensity to bronchospasm may provoke an attack. When i / m administration may infiltrate at the injection site.

Overdosing Symptoms: nausea, vomiting, gastralgia, oliguria, hypothermia, lowering blood pressure, tachycardia, shortness of breath, tinnitus, drowsiness, delirium, impaired consciousness, acute agranulocytosis, hemorrhagic syndrome, acute renal and / or hepatic impairment, convulsions, paralysis, respiratory . muscle Treatment: induction vomiting, chrezzondovoe gastric lavage, saline laxatives, activated carbon; carrying out forced diuresis, hemodialysis, in the development of convulsions – in / diazepam and barbiturates fast.

Interaction with other medicinal products
due to the high probability of pharmaceutical incompatibility can not be mixed with other drugs in the same syringe. It enhances the effects of ethanol; simultaneous application of chlorpromazine and other phenothiazine derivatives can lead to severe hyperthermia.
Radiopaque substances, colloidal blood substitutes and penicillin should not be used during treatment anadrol. When concomitant administration of cyclosporine snizhaetdya concentration of the latter in the blood. anadrol, displacing connection with protein oral hypoglycemic drugs, indirect anticoagulants, steroids and indomethacin, increases their activity. Phenylbutazone, barbiturates and other gepatoinduktory while appointing reduce the effectiveness anadrol. Co-administration with other non-narcotic analgesics, tricyclic antidepressants, contraceptive hormonal agents and allopurinol may lead to increased toxicity, Sedatives and tranquilizers increase the analgesic effect anadrol. Tiamazol sarkolizin and increase the risk of leukopenia. The effect of increasing codeine, histamine H2-blockers and propranolol (slow inactivation). Myelotoxic drugs increase the expression gematotoksichnosti anadrol.

Specific guidance
in the treatment of children under 5 years and patients receiving cytotoxic agents, receiving dipyrone should be done only under medical supervision. In patients with atopic asthma and hay fever have an increased risk of developing hypersensitivity reactions. With long-term (more than a week) the application necessary to monitor patterns of peripheral blood and functional state of the liver. In patients receiving dipyrone may develop agranulocytosis, and therefore, the detection of unmotivated rise in temperature, chills, sore throat, difficulty swallowing, stomatitis, as well as the development of vaginitis or proctitis require immediate removal of the drug. Intolerance occurs rarely, but the shock of a threat after the on / in the preparation is relatively higher than after oral administration of the drug. It is not permissible to use to relieve acute pain in the abdomen (to determine the cause). When i / m administration is necessary to use a long needle.

Product form
The solution for in / in / m of 250 mg / ml or 500 mg / ml (ampoules) – 1 or 2 ml. 10 ampoules with a knife or lancet ampulnam and instructions for use in a pile of cardboard.
On 5 vials in blisters. On 2 blisters with a knife or lancet ampulnam and instructions for use in a pile of cardboard. When packing vials with a point or ring fault knife scarifier ampoule or do not invest. buy steroid pills online clenodex supplements like steroids