anadrol results

Treatment anadrol results TC hypogonadal men dose-dependently restores to normal total testosterone levels in serum and levels of bioavailable testosterone treatment increases the content of dihydrotestosterone (DHT) and estradiol (E2) serum content decrease globulin sex hormone binding (SHBG ), luteinizing hormone (LH) and follicle stimulating hormone (FSH). As boys and adult men with ptogonadizmom treatment TK anadrol results leads to a decrease in the symptoms of testosterone deficiency. Moreover, treatment increases bone mineral density and lean body mass (body mass by reducing fat). Treatment improves sexual function, including libido and potency.
The treatment dose dependently decreases the content of high density lipoprotein (HDL), low density lipoprotein (LDL) and triglycerides, increases levels of hemoglobin and hematocrit, as well clinically insignificant change in the content of liver enzymes, and prostate specific antigen . Treatment may lead to an increase in prostate size, but the side effects of prostate were observed. In patients with hypogonadism and diabetes, there was an increase in insulin sensitivity and a decrease in blood glucose levels.
The boys with delayed growth and puberty, treatment with anadrol results TC initially accelerate the growth and development of secondary sexual characteristics.
In women, ovariectomized with treating only estrogen adding anadrol results TC increases libido, increased bone mineral density and reduced body fat mass. At transgender (of women in men) treatment increases the TK anadrol results masculinization.

Pharmacokinetics Absorption After oral administration of testosterone undecanoate significant part together with a lipophilic solvent absorbed in the small intestine and into the lymph system, thus partially bypassing initial passage through the liver. TK anadrol results ® should be taken with food to improve absorption. Bioavailability is about 7%. Distribution Of lymphatic system undecanoate testosterone and hydrolysed to testosterone. A single dose of 80 to 160 mg anadrol results TC ® results in a clinically significant increase in the total testosterone concentration in plasma, with a maximum concentration of about 40 nmol / l (Cmax) achieved after about 4-5 hours (t max ) after administration. Increased testosterone concentration in the blood plasma remains for at least 8 hours. Testosterone and testosterone undecanoate display a high level (over 97%) of non-specific protein binding kroviiGSPG. Metabolism In plasma and tissues testosterone undecanoate is hydrolyzed to the natural male androgen -testosterone.Testosterone is further metabolized to dihydrotestosterone and estradiol. Elimination Testosterone, estradiol and dihydrotestosterone are metabolized by conventional means. Elimination occurs mainly via the urine as conjugates (etioholanolon and androsterone). Linearity The linearity of dosing has been demonstrated for doses of 40 to 240 mg / day.

Indications

Testosterone replacement therapy in males for conditions associated with primary and secondary hypogonadism, both congenital and acquired.

Contraindications

 

  • Having now or history of prostate or breast cancer;
  • Hypersensitivity to any components of the preparation.
    If you have one of these diseases, before taking this medication, you should consult with your doctor.The caution
    in patients with previous heart disease, kidney or liver disease treated with androgens may cause complications characterized by edema with or without congestive heart failure.
    There is no exact data and recommendations on the safety of treatment with testosterone esters men sleep apnea. Needed weighted clinical judgment and caution in patients with the presence of risk factors such as obesity or chronic lung disease.
    When the side effects associated with treatment with androgens, taking anadrol results TC ® should stop or reduce the dose.
    If you have one of these diseases, before taking the drug should consult a doctor.Dosing and Administration
    Dose picked individually, depending on the clinical effect.
    Admission for adults:
    In general, the initial dose is 120-160 mg daily for 2-3 weeks. The maintenance dose of 40-120 mg per day, its choice should be based on the clinical effects obtained in the first weeks of therapy. To improve the absorption of the drug should be taken during meals with a little water. The capsules should be swallowed whole without chewing. It is advisable to take the first half of the dose in the morning and half in the evening. If it is an odd number of capsules, the higher the dose should be taken in the morning.

    Side effects
    The following adverse reactions have been associated with androgen therapy:

     

    Class system / organ MedDRA term
    Neoplasms benign, malignant and unspecified (including cysts and polyps) Prostate cancer (progression of subclinical prostate cancer)
    Disorders of the circulatory and lymphatic systems polycythemia
    Disorders of metabolism and nutrition fluid retention
    Psychiatric disorders Depression, nervousness, mood disturbances, libido increased, libido decrease
    Violations of the musculoskeletal – and connective tissue myalgia
    Vascular disorders hypertension
    Gastrointestinal disorders Nausea
    Violations of the skin and subcutaneous tissue The itch, acne
    Violations of the reproductive system and breast Gynecomastia, oligospermia, priapism, increased prostate size
    research Abnormal hepatic studies lipids (decrease in HDL, LDL, triglycerides in plasma), the increase in the concentration of prostate specific antigen

    Some patients may experience diarrhea, and pain or discomfort in the stomach area while taking anadrol results TC.
    If any of these instructions side effects are compounded, or if you notice any other side effects not mentioned in the instructions, inform your doctor.

    Overdose
    . The acute toxicity of testosterone have not expressed
    Overdose TK anadrol results may cause gastro-intestinal disturbances in connection with the content of castor oil.
    Treatment: gastric lavage, symptomatic treatment.

    Interaction with other drugs
    Inductors microsomal oxidation enzymes may decrease and enzyme inhibitors of microsomal oxidation may increase testosterone levels. Hence, while the reception, the dose should be adjusted anadrol results TC.
    Androgens can increase glucose tolerance and reduce the need for insulin or other antidiabetic drugs. Androgens may enhance the anticoagulant effect of coumarin-type, which allows to reduce the dose of these funds.

    Specific guidance
    should be monitored following parameters in people taking anadrol results LC ® (the first year of admission – quarterly, then once a year):

  • digital rectal prostate study and the level of prostate specific antigen;
  • hematocrit and hemoglobin levels to exclude polycythemia.
    The boys at prepubertal should monitor the increase in growth and sexual development, as TK anadrol results ® in high dosages may accelerate epiphyseal closure and sexual maturation.Composition
    Capsules 40 mg.
    10 capsules in blister PVC / A1. 1 blister in a hermetically sealed sachet made of laminated aluminum foil. At 3, 6 or 12 is placed in a sachet pack carton along with instructions for use.

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